A beloved Missouri couple is thought to be swept away in a record-breaking deadly storm, but when a closer look at the family farm points to foul play, law enforcement searches for clues long since washed away.

When a Michigan mother disappears on an afternoon walk, investigators pin all hope on their sole eyewitness: a 10-year-old boy who may have witnessed the unthinkable.

When a successful Arizona businesswoman disappears on a holiday shopping trip, investigators hunt for a kidnapper; when the killer takes his secrets to the grave, however, the only chance of finding her is a psychic's mysterious vision.

A young couple sets out from a holiday visit but never make it home as law enforcement search dangerous terrain fraught with derelict silver mines. In the black night and bitter cold, what happens when no one can hear you scream?

A spunky grandmother and former bail bondswoman is a no-show at work, leaving friends and family desperate for answers.

When a California mother wakes to find the door wide open and her daughter missing, law enforcement travel the country to find her until they discover a dark plot that began at the teen's doorstep.

When a widower disappears from his Southern California home, investigators find themselves caught up in a federal investigation involving the infamous hunt for skyjacker D.B. Cooper.

When a promising forensics student is found mutilated on a lonely stretch of Utah motorway, her Sheriff's department colleagues will stop at nothing to deliver justice.

Detectives attempt to trace a young woman's last steps as she leaves a casino and disappears into the night. An almost forgotten childhood memory helps find her buried in the backyard.

When a young South Carolina father goes missing, investigators must navigate a twisting trail of small-town rumors and misguided revenge to uncover the deadly truth.

When a Texas father disappears without a trace, investigators go on an international manhunt to catch a killer and unravel a sinister plot that has them searching for answers deep into the Chihuahuan Desert.

A retiree settles in Southern California hoping to live his best life; when he disappears without a trace, investigators must uncover if his demise was connected to the unconventional pen pals he made.

A beloved mother is found brutally murdered near the military town of North Pole, Alaska, and soon four more girls meet the same fate.

A champion Russian boxer disappears from Brighton Beach, N.Y., and the neighbourhood dare not talk for fear of reprisal until investigators uncover a long-buried secret in a New Jersey backyard.

After two Colorado women vanish in a deadly winter storm, key evidence keeps the case open for investigators to uncover the truth; a harrowing blizzard rescue the very same night could hold the clues to an almost 40-year search for the killer.