Farmer Vernon Diggins in South Africa is attacked by a Mozambique spitting cobra that was curled up under his pillow; his middle finger nearly needed amputation. Nick Greeve is on a rafting trip in Utah when he is attacked by a black bear. His friends must row him 60 miles ,over rapids and in the soaring heat, to help, while he is bleeding to death.

While doing yard work after Hurricane Katrina, teenager Patrick Dodson accidentally rips a bag full of mulch and fire ants, the contents of which are sprayed all over his legs. He suffers an allergic reaction and nearly dies. Game ranger Rudi Lorist is leading tourists through the wilderness in South Africa, when he is charged by a lioness. He shoots it once, then it gets up again and catches him off-guard.

A wildlife specialist and helicopter crash survivor Pieter Aansluit is charged by an elephant which overturns his truck, leaving him trapped underneath. Eric Ebinger is stricken by a prairie rattlesnake while camping, and his son Rio, just 10 years old, must row him one and a half hours upstream to help.

Teenager Hoku Aki is mauled by a tiger shark while surfing in Hawaii, and loses his leg below the knee; Gerald Marois climbs a tree to escape from a black bear, which promptly brings him down and gores him.

Two students, Rusty van Wert and Caleb Snow, are bitten by a cottonmouth snake after it was misidentified by a teacher and allowed to be a class pet. A Marine, Cpl. Justin Trinidad, saves couple Patricia and Javier Franco from a bull hippo in Zimbabwe after they fall from their boat.

Colton Reeb is attacked by a cougar on a camping trip, and Robbie Hamouda is bitten by a redback spider after he and a friend become lost in the Australian Outback.